Yo mama is so fat...that she should really consider a diet and maybe consider medical advice.
Yo mama is so ugly...that I expect she sometimes finds it difficult attracting men, however she has a great personality, which really makes up for her ugliness.
Yo mama is so stupid.....that I expect she probably needs to consider some adult education classes.
Yo mama is so skinny.....that maybe you should discuss with her the dangers of over dieting and of course advise her to maybe see a therapist who could curtail the potential anorexia that may result of this undereating.